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What MRM involves

Modified radical mastectomy removes all breast tissue along with the axillary lymph nodes at levels I and II. The chest wall muscles (pectoralis major and minor) are left intact. This is the key difference from the older classical radical mastectomy, which removed the muscles and left patients with significant chest wall deformity.

The operation removes the breast, the skin overlying it, the nipple-areola complex, and the lymph nodes from the armpit on the same side. It is performed under general anaesthesia and takes approximately two to three hours.

When MRM is recommended

MRM is considered when the cancer has spread to the axillary lymph nodes, when the tumour is large relative to the size of the breast, or when breast-conserving surgery is not possible. Common situations include:

  • Node-positive breast cancer confirmed on imaging or biopsy
  • Large tumours where removing adequate margins would leave an unacceptable cosmetic result
  • Inflammatory breast cancer, where mastectomy is the standard surgical approach
  • Patients who prefer mastectomy after being counselled about all options
  • Locally advanced breast cancer after neoadjuvant chemotherapy

How MRM differs from simple mastectomy

A simple (or total) mastectomy removes the breast tissue without formally dissecting the axillary lymph nodes. MRM goes further by also clearing levels I and II of the axilla. If you have confirmed node involvement, MRM gives your surgeon more complete information about how far the cancer has spread, which guides decisions about further treatment.

What happens during surgery

You will be under general anaesthesia for the procedure. Dr. Shruthi makes an elliptical incision across the breast, removes all breast tissue down to the chest wall muscle, and then extends the dissection into the axilla to remove the lymph nodes. The wound is closed in layers and a drain is placed to prevent fluid collecting.

The whole operation takes two to three hours. You will wake up with a flat chest on the operated side, one or two surgical drains, and a dressing over the wound. Most patients are comfortable with pain medication within a day of surgery.

Recovery after MRM

Most patients stay in hospital for two to three days. The drain is removed when the fluid output drops to an acceptable level, usually within one to two weeks at home. You will be taught how to care for the drain and how to recognise early signs of infection before you leave hospital.

Arm and shoulder movement exercises start the day after surgery. These are important. Early movement prevents the stiffness and tightness that can develop when the arm is rested for too long. Most patients return to light daily activity within three to four weeks.

  • Hospital stay: 2 to 3 days
  • Drain removal: 1 to 2 weeks after surgery
  • Light activity: 3 to 4 weeks
  • Return to full activity: 6 to 8 weeks, depending on any additional treatment

Reconstruction after MRM

Breast reconstruction can be performed at the same time as MRM (immediate reconstruction) or in a planned second operation after you have completed other treatments like radiotherapy (delayed reconstruction). Both are valid paths and the right choice depends on your cancer treatment plan, your body, and your preferences.

Options include implant-based reconstruction (sub-pectoral or pre-pectoral), the latissimus dorsi flap from the back, or chest wall perforator flaps. Dr. Shruthi discusses all options before surgery so you can make an informed decision that feels right for you.

If you are considering reconstruction, it is best to have that conversation before MRM, not after. Planning reconstruction at the time of mastectomy gives you more options and often a better final result.

Dr. Shruthi's approach

Before recommending MRM, Dr. Shruthi always reviews whether breast-conserving surgery is possible for you. She looks at the size and location of the tumour, the size of your breast, and whether the margins can be cleared safely. If conservation is genuinely possible, she will explain that clearly.

When MRM is the right operation, she focuses on making the experience as manageable as possible, including planning reconstruction where you want it, and making sure you understand every step of what comes next.

Frequently asked questions

Have a breast health concern?
Get a specialist's assessment.

Dr. Shruthi Neela is available at Sindhu Hospitals, HITEC City, Monday to Saturday.